Category: Job posting

Company Overview
Orum Therapeutics is a private biotech company located in Daejeon, Korea, and Cambridge, Massachusetts. We are developing a novel class of therapeutics to bring new medicines to patients with unmet medical needs. Orum leverages its proprietary antibody and conjugation platforms to inhibit or degrade intracellular target proteins. We are advancing our first set of oncology candidates toward preclinical development.

Role Description
Orum Therapeutics is seeking a motivated Project Manager (PM) to join as a key member of our R&D teams. The candidate, working with the Project Leader (PL), will be responsible for planning and managing the project execution from target discovery through to preclinical development with the details. Critical to success is a thorough understanding of the drug development process and a strong ability to organize, prioritize and navigate tasks through the challenges.

KEY RESPONSIBILITIES
● Catalyze and nourish the efforts of our highly talented global project team through the journey of drug discovery and development
● Create and maintain the project progress and resource allocation by relevant communication tools (including the Gantt, action item tracker, etc.) and communicate with the team to support the research goal achievement
● Coordinate team meetings and provide regular timeline update, create agendas/minutes and ensure critical actions items are addressed in a timely manner
● Facilitate alignment and cross-functional collaboration between discovery, late phase research, CMC and preclinical to enable the team to deliver outcomes within timelines
● Provide operational leadership and establish processes to execute on program strategy

Requirements and Qualifications
● Relevant Scientific Degree (BS or MS)
● Work experience in the biotech/pharmaceutical industry not required but preferred
● Highly motivated and capable to work independently and as part of the team
● Excellent interpersonal, organizational, verbal and written communication skills
● Is innovative and entrepreneurial and enjoys working in a fast-paced, international, rapidly growing company environment.

Please send your resume and cover letter to jobs@orumrx.com to apply
(Title field: Full Name_Project Manager)

Ciscovery Bio is inviting a Research Scientist to work on our noncoding genome-driven Precision Medicine research projects.

Job description

About Ciscovery Bio (https://www.linkedin.com/company/ciscovery-bio-inc)

Ciscovery Bio Inc. is a biotech startup specializing in the discovery and commercialization of noncoding biomarkers using its proprietary discovery platform for gene regulatory elements. We are committed to providing a motivating work environment while simultaneously emphasizing a healthy work-life balance.

The Opportunity:

We are seeking a talented scientist to join our interdisciplinary team in Philadelphia, PA. This position will play a critical role in generating and testing hypotheses on drug toxicity and efficacy tests in multiple cellular, pathological or genetic background. As an early member of the team, the candidate will work alongside founders and will be afforded the opportunity to make a broad impact on the future of the company.

Job Responsibilities and Expectations:

-Plan and conduct cell culture-based discovery/manipulation of noncoding biomarkers
-Participate in the generation of sequencing libraries
-Participate in the biological interpretation of data
-Participate in the production of biomarker panels
-Participate in grant writing and preparation of presentations to stakeholders
-Participate in journal clubs to stay current with respect to new and relevant technologies/discoveries
-Be attentive to detail in data recording and analysis
-Maintain well-organized lab notebooks following the company guidelines
-Present data and communicate effectively
-Work efficiently with external partners
-Work alongside senior leaders to deliver set milestones of the company

Candidate Qualifications:

– Ph.D. in Cancer Biology, Cell and Molecular Biology, Genomics, Systems Biology or a related discipline with ≥0 year of postdoc experience
-Must be proficient in conducting mammalian tissue culture, molecular cloning, RNA extraction, QPCR, electroporation, and standard molecular biology techniques
-Show aptitude for problem solving and decision making based on quantitative data
-Possess strong verbal and written communication skills

Benefits:

-Competitive base pay
-Stock options
-Health insurance support

Review will begin on 11/1/2020 until the position is filled.

Contact:

Please email a cover letter with a CV and two references to joonyul.kim@cscovery.com.

테라이뮨에서 Engineered T cell을 이용하여 B-cell lymphoma 치료제 개발 연구를 함께 하실 프레시 박사 (2년 경력 이내) 분을 모집하고 있습니다.

Job Description
Title: Scientist I
Division: Research and Development
Type of employment: full-time, annual employment renewal
Available number of positions: 1
Deadline for applications: 9/11/2020

The successful candidate will put his or her research efforts in the discovery and development of immune cell derived therapeutics for the treatment of B-cell lymphomas. S/he will participate as a team member driving research programs forward the development and discovery of proof of concept studies of new pipelines of the business as well as research programs across different stages of pre-clinical live cell therapeutics. The successful candidate must be motivated to design, execute, and interpret studies for the development of a new therapeutics, and also validation and characterization of engineered immune cell therapeutic products but not limited. The fellow is encouraged to effectively and frequently collaborate with multidisciplinary teams.

About the Company:
TeraImmune, Inc. is a Maryland-based startup company developing immune therapeutics using regulatory T cells (Tregs). By combining target specific receptors with Tregs, the company provides CAR-Treg and TCR-Treg technologies to help the patients with autoimmune diseases. In addition to Treg immunology, TeraImmune is expanding its range of scope in immune therapies to other immune cells and biologics as well as cancer therapeutics. TeraImmune is now looking for enthusiastic and motivated scientists to prepare the first-in-human clinical trials with the gene engineered Tregs followed by anti-cancer therapy.

Primary responsibilities (include, but are not limited to):
The successful candidate must lead a project as a scientist to develop an anti-cancer cell therapy. Expertise to design, perform and interpret data in vitro and ex vivo experiments with experience in immunology, cancer biology or cell biology is required. Proficiency in cell biology assays that may include flow cytometry, ELISA, cell proliferation, cellular cytotoxicity, immune cell isolation from whole blood or tissues, cell culture, transfection and cloning to generate stable cell lines is expected but not necessary. Previous experience with T cell biology with characterization of immune cell subsets is highly desirable. Analyzing and presenting data in peer-reviewed journals or conferences is required. Working independently to manage time and multiple experiments simultaneously is necessary for this position.
Successful candidate may have to contribute to various projects outside of his/her own and collaborate with stakeholders from all relevant functions and must demonstrate clear and professional verbal and written communication skills.

Basic Requirements
The candidate should hold an MD, PhD or DVM degree with less than 2 years of experience or acquiring the degree before hiring with wet lab experience. The successful candidate is expected to have experiences in performing progressive and advanced duties, or the equivalent training/experience. Strong knowledge on cell biology or immunology with understanding and performing flow cytometry is a big plus. Previous experience in tissue culture is highly expected.

Benefits
The company fully supports health and dental insurance as a group. If required, the company is willing to petition VISA or green card application, but the applicant is responsible for the processing and legal fee.

If you are interested in TeraImmune, please email a cover letter containing your interest experiences with a separate CV or resume as well as the contact information of at least two referees to HR manager at recruiting@teraimmune.com. Please feel free to email the HR manage with any questions.
For more information, please see website: www.teraimmune.com

Job Description:
Title: Research associate
Division: R&D
Type of employment: full-time
Available number of positions: 2

The candidate will join the research efforts in the discovery and development of immune cell derived therapeutics for the treatment of autoimmune diseases. S/he will be part of a team driving forward research programs across the different stages of pre-clinical live cell drug discovery. Responsibilities include the design, execution, and interpretation of studies for the validation and characterization of engineered immune cell therapeutic products. The scientist will effectively and frequently collaborate with colleagues in the present scientific results to multidisciplinary teams.

The Company:
TeraImmune, Inc. is a Maryland-based startup developing immune cell therapies using regulatory T cells (Tregs). By combining target specific receptors with Tregs, the company provides CAR-Treg and TCR-Treg technologies to help the patients with autoimmune diseases. TeraImmune is now looking for enthusiastic and skillful researchers to prepare the first-in-human clinical trials with the gene-engineered Tregs.

Primary responsibilities (include, but are not limited to):
Ability to design, perform and interpret data in vitro and ex vivo experiments. Proficient in cell biology assays that could include flow cytometry, ELISAs, cell proliferation, cellular cytotoxicity, immune cell isolation from whole blood or tissues, cell culture, transfection and cloning to generate stable cell lines. Previous experience with cytokine profiling with flow cytometry is desirable. Characterization of immune cell subsets e.g., regulatory T cells. Ability to analyze and present data in professional publication ready format and work independently to manage multiple experiments simultaneously.
Candidate will contribute to various projects outside of his/her own and collaborate with stakeholders from all relevant functions and must demonstrate clear and professional verbal and written communication skills.
Typically, the candidate should have an M.S. with 3-5 years of experience, or a B.S./B.A. with 4-6 years of experience, performing progressively advanced duties, or the equivalent training/experience. Strong cell biology and understanding of flow data skills are required. Previous experience of tissue culture is required. A good background in immunology is desirable. Prior laboratory experience is preferred.

Benefits:
The company fully supports group medical, prescription and dental insurance. If required, the company can sponsor VISA or green card application, but the applicant is responsible for the processing and legal fee.
If you are interested in joining TeraImmune, please email Jay Park at jpark@teraimmune.com.
Website: www.teraimmune.com

* TeraImmune, Inc. is an equal opportunity employer committed to employing a diverse workforce, including, but not limited to, minorities, females, individuals with disabilities, protected veterans, sexual orientation, gender identity Equal Employment Opportunity is The Law

Positions available in following specialty discipline:

• Genomics
• Microbiome Research and Development
• Clinical Genomics
• Bioinformatics

Psomagen, Inc. is a genomic sequencing and data analysis company that offers advancements in translational research, precision medicine, biomedical research, and agricultural science. Psomagen is looking to further expand the capabilities in the healthcare space in addition to the current diagnostic kit and at-home testing kit for genetic traits and microbiome profiling in CLIA-certified and CAP-accredited laboratories.

Through in-depth research and exploration within the field of genetics, Psomagen has identified the most effective techniques for DNA testing and stays updated on all of the latest updates in gene technology, regularly participating in major global research studies. Psomagen, Inc. was established in 2004 in Rockville, MD and has been working with some of the top research organizations and facilities in the country including multiple institutes of National Institutes of Health (NIH), Johns Hopkins University, and many research centers and healthcare organizations around the globe.

With the recent IPO listing via KOSDAQ, Psomagen is rapidly expanding research and product development capacity for genetic and microbiome test market both in direct-to-consumer and clinical space. We are looking for talents to join us during this exciting time of expansion.

Responsibilities

• Strong domain knowledge in genomics, excellent programming skills, and experience applying that knowledge with next generation sequencing technologies
• To combine research in microbiology, medicine, health-related studies with information technology to develop strategic and tactical plan toward genetic testing product development
• To analyze shotgun metagenomic dataset from human-associated microbiome attributed to health and disease status
• Scientific collaborations with physicians and scientists for clinical studies
• Working closely with software developers to integrate research finding toward product development

Qualifications

• Must be highly motivated and have strong ability to develop and maintain effective relationships with colleagues and customers
• Ability to work effectively in a fast-paced, team environment
• Minimum of three years of practical experience working in NGS technologies is preferred
• Good understanding of genomics, molecular biology, microbiology, and technologies such as microarray and next-generation sequencing
• Experience with variation analysis from next-generation sequencing data (Whole Genome Sequencing, Whole Exome Sequencing, RNA sequencing, 16S sequencing and Whole metagenome sequencing)
• Must be able to work effectively both independently and as a team player
• Excellent written and verbal communication skill
• Ability to analyze, manage, interpret, visualize and illustrate scientific data
• Self-directed and highly adaptable and collaborative

Education

• Ph.D. (or MS with 3+ years of relevant experience, or BS with 5+ years of relevant experience) in life sciences including computational biology, bioinformatics, and statistics
• Medical Technologist is strongly preferred

Contact: Jiwon Lee (jwlee@psomagen.com)